ChemicalBook > CAS DataBase List > ABX-1431
ABX-1431
- Product Name
- ABX-1431
- CAS No.
- 1446817-84-0
- Chemical Name
- ABX-1431
- Synonyms
- CS-2856;ABX-1431;Elcubragistat;ABX1431;ABX 1431;ABX-1431,inhibit,ABX 1431,Monoacylglycerol lipase,ABX1431,MAGL,Inhibitor;1,1,1,3,3,3-Hexafluoro-2-propyl 4-[2-(1-Pyrrolidinyl)-4-(trifluoromethyl)benzyl]piperazine-1-carboxylate;1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate;1,1,1,3,3,3-hexafluoropropan-2-yl 4-{[2-(pyrrolidin-1-yl)-4-(trifluoromethyl)phenyl]me thyl}piperazine-1-carboxylate;1-Piperazinecarboxylic acid, 4-[[2-(1-pyrrolidinyl)-4-(trifluoromethyl)phenyl]methyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester
- CBNumber
- CB74667484
- Molecular Formula
- C20H22F9N3O2
- Formula Weight
- 507.39
- MOL File
- 1446817-84-0.mol
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ABX-1431 Property
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (>25 mg/ml)
- form
- solid
- color
- White
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 26023
- Product name
- ABX-1431
- Packaging
- 1mg
- Price
- $49
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 26023
- Product name
- ABX-1431
- Packaging
- 50mg
- Price
- $1184
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 26023
- Product name
- ABX-1431
- Packaging
- 5mg
- Price
- $179
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 26023
- Product name
- ABX-1431
- Packaging
- 10mg
- Price
- $333
- Updated
- 2024/03/01
AK Scientific
- Product number
- 0863DV
- Product name
- CID71657619
- Packaging
- 10mg
- Price
- $245
- Updated
- 2021/12/16
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ABX-1431 Chemical Properties,Usage,Production
Description
ABX-1431 (1446817-84-0) is a potent (IC50 = 14 nM in vitro, 2.2 nM in human PC3 cells) and very selective (>100-fold over hABHD6, >200-fold over hPLA2G7) inhibitor of monoacylglycerol lipase (MAGL).1 Active in a rat formalin pain test at 3mg/kg. Orally bioavailable and CNS penetrant.
References
1) Cisar et al. (2018), Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders; J. Med. Chem., 61 9062
ABX-1431 Preparation Products And Raw materials
Raw materials
Preparation Products
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ABX-1431 Suppliers
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6393
- Advantage
- 58
- Tel
- +1 (732)236-3202
- sales@cckinase.com
- Country
- United States
- ProdList
- 2738
- Advantage
- 58
- Tel
- +1-833-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57511
- Advantage
- 58
- Tel
- +1-781-999-5354
- support@targetmol.com
- Country
- United States
- ProdList
- 19973
- Advantage
- 58
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